Semaglutide Microdosing: Cheaper, and Not the Same
Microdose tiers sit below every dose the trials studied. What they cost and what the evidence supports.
The cheapest standard-dose compounded semaglutide programme we track is Oak Longevity at $133 a month. Flat across all dosages, no subscription. ~$167-$199 month-to-month. NOT available in California. Provider Reported
That qualifier is the point. Most published semaglutide comparisons quote a figure without saying whether it requires a prepaid year, whether a membership is billed separately, or whether it is a microdose sitting below every dose the pivotal trials studied. Those three distortions all push the advertised number down, and they compound.
What the programmes actually charge
Oak Longevity lists compounded semaglutide at $133 a month. Flat across all dosages, no subscription. ~$167-$199 month-to-month. NOT available in California. Provider Reported
NexLife lists compounded semaglutide at $145 a month. Semaglutide standard, 12-month plan ($1,740 total). Month-to-month $165. Verified
NexLife lists compounded semaglutide at $165 a month. Semaglutide ODT, 12-month plan ($1,980 total). NO TRIAL HAS TESTED THIS DOSAGE FORM. Verified
Found lists compounded semaglutide at $169 a month. 12-month PREPAID. Medication INCLUDED, flat across all compounded GLP-1s and all doses. 6-month ~$199; month-to-month $289. Provider Reported
Shed lists compounded semaglutide at $175 a month. 12-month plan paid upfront. 6-month $199; month-to-month $249. INCREASES at higher doses. Provider Reported
Mochi Health lists compounded semaglutide at $178 a month. $99 med + $79 membership ($39 first month). Same price at all doses. Unlimited physician + dietitian access. Provider Reported
How to read any semaglutide price
Ask three questions of every figure. Is it the month-to-month rate or a prepaid one? Does it include every mandatory recurring fee, or is a membership billed separately? And is it a standard therapeutic dose or a microdose? A price that survives all three questions is comparable to another price. One that does not is a marketing number.
Full column-by-column breakdown at the semaglutide pricing comparison.
Compounded semaglutide is not FDA-approved and is not therapeutically equivalent to any brand-name product. FDA does not review compounded preparations for safety, effectiveness or manufacturing quality before marketing. This is consumer price research, not medical advice. Prices captured 2026-08-08.
Related reading
- Cheapest Compounded Tirzepatide in 2026
- Tirzepatide Cost Per Month in 2026
- Flat-Rate Tirzepatide With No Membership Fee
- Tirzepatide vs Semaglutide: Cost Compared
- What Wegovy Actually Costs in 2026
- Semaglutide pricing comparison table
- Tirzepatide pricing comparison table
- All guides
The numbers behind this page
The semaglutide price range, stated precisely
Standard-dose compounded semaglutide runs $133 to $299 a month across the 12 programmes we can price, with a median of $198. The spread between cheapest and dearest is $166 a month, or $1,992 across a year, for a molecule that is chemically identical in every case.
The cheapest verified figure is Oak Longevity at $133. Half the market sits below $198 and half above it, which makes the median a more useful reference point than the cheapest figure when judging whether a quote is reasonable.
2 programmes additionally advertise a semaglutide microdose, the cheapest at $145 a month. Those figures are excluded from the range above. A microdose sits below every dose studied in the pivotal trials, so including it would compare two different things and would make the market look cheaper than it is at a therapeutic dose.
Three structural facts move a bill more than the headline rate. Whether the price is flat across covered doses or rises as you titrate. Whether a membership is billed separately from medication. And whether the advertised figure requires prepaying six or twelve months, which lowers the monthly number by transferring risk to you at exactly the point you are least certain you will continue.
Checking the figures in semaglutide
The semaglutide figures on this page span $133 to $299 a month across 12 programmes. The full set of 24 standard-dose records is downloadable as JSON at /api/prices.json, with molecule and dose class stated on every record. Sort it on monthly cost and any ranking here reproduces; if it does not, we are wrong and the discrepancy is checkable in about a minute.
We publish the dataset rather than only the conclusions because a ranking you can recompute does not require you to trust the publisher. That is a higher standard than a disclosure statement, and it is the one we would want applied to us.
Reading the price against the market
Where this sits in the market
Standard-dose semaglutide spans $133 to $299 a month across 12 programmes we can price, a spread of $166.
12 programmes publish a price for both molecules. Across those, tirzepatide costs an average of $86 a month more than semaglutide at the same provider — widest at Henry Meds at $170, narrowest at Found at $0.
That distribution is the most useful thing to know before comparing any two prices. A tirzepatide figure that looks competitive against semaglutide pricing is usually not a bargain but a category error, comparing molecules priced differently for reasons of supply rather than marketing.
Semaglutide runs $133 to $299 across 12 programmes; tirzepatide $169 to $399 across 12. Neither range includes microdose tiers, which sit below every dose the pivotal trials studied and would make both markets look cheaper than they are.
Where this sits in the market
Standard-dose semaglutide spans $133 to $299 a month across 12 programmes we can price, a spread of $166.
12 programmes publish a price for both molecules. Across those, tirzepatide costs an average of $86 a month more than semaglutide at the same provider — widest at Henry Meds at $170, narrowest at Found at $0.
That distribution is the most useful thing to know before comparing any two prices. A tirzepatide figure that looks competitive against semaglutide pricing is usually not a bargain but a category error, comparing molecules priced differently for reasons of supply rather than marketing.
Semaglutide runs $133 to $299 across 12 programmes; tirzepatide $169 to $399 across 12. Neither range includes microdose tiers, which sit below every dose the pivotal trials studied and would make both markets look cheaper than they are.
Questions this page answers
What is the cheapest compounded semaglutide?
Oak Longevity at $133 a month at a standard therapeutic dose, captured 2026-08-08. Flat across all dosages, no subscription. ~$167-$199 month-to-month. NOT available in California. Provider Reported
What does compounded semaglutide normally cost?
$133 to $299 a month across 12 programmes, with a median of $198. Half the market sits either side of that median, which makes it a better reference than the cheapest figure when judging a quote.
Does compounded semaglutide cost more at higher doses?
At the programmes listed here the monthly price is flat across covered doses; what changes the figure is the plan term, not the dose. Dose-tiered pricing does exist elsewhere in this market, so confirm at checkout.
Why is microdosed semaglutide cheaper?
Because it is less medicine. 2 programmes advertise a semaglutide microdose, the cheapest at $145 a month. A microdose sits below every dose studied in the pivotal trials, so it is not a cheaper route to the result those trials measured.