The STEP 1 Trial: What It Actually Showed
Semaglutide 2.4mg against placebo over 68 weeks, the side-effect profile, and what the result does not promise.
The cheapest standard-dose compounded semaglutide programme we track is Oak Longevity at $133 a month. Flat across all dosages, no subscription. ~$167-$199 month-to-month. NOT available in California. Provider Reported
That qualifier is the point. Most published semaglutide comparisons quote a figure without saying whether it requires a prepaid year, whether a membership is billed separately, or whether it is a microdose sitting below every dose the pivotal trials studied. Those three distortions all push the advertised number down, and they compound.
What the programmes actually charge
Oak Longevity lists compounded semaglutide at $133 a month. Flat across all dosages, no subscription. ~$167-$199 month-to-month. NOT available in California. Provider Reported
NexLife lists compounded semaglutide at $145 a month. Semaglutide standard, 12-month plan ($1,740 total). Month-to-month $165. Verified
NexLife lists compounded semaglutide at $165 a month. Semaglutide ODT, 12-month plan ($1,980 total). NO TRIAL HAS TESTED THIS DOSAGE FORM. Verified
Found lists compounded semaglutide at $169 a month. 12-month PREPAID. Medication INCLUDED, flat across all compounded GLP-1s and all doses. 6-month ~$199; month-to-month $289. Provider Reported
Shed lists compounded semaglutide at $175 a month. 12-month plan paid upfront. 6-month $199; month-to-month $249. INCREASES at higher doses. Provider Reported
Mochi Health lists compounded semaglutide at $178 a month. $99 med + $79 membership ($39 first month). Same price at all doses. Unlimited physician + dietitian access. Provider Reported
How to read any semaglutide price
Ask three questions of every figure. Is it the month-to-month rate or a prepaid one? Does it include every mandatory recurring fee, or is a membership billed separately? And is it a standard therapeutic dose or a microdose? A price that survives all three questions is comparable to another price. One that does not is a marketing number.
Full column-by-column breakdown at the semaglutide pricing comparison.
Compounded semaglutide is not FDA-approved and is not therapeutically equivalent to any brand-name product. FDA does not review compounded preparations for safety, effectiveness or manufacturing quality before marketing. This is consumer price research, not medical advice. Prices captured 2026-08-08.
Related reading
- Semaglutide Microdosing: Cheaper, and Not the Same
- Cheapest Compounded Tirzepatide in 2026
- Tirzepatide Cost Per Month in 2026
- Flat-Rate Tirzepatide With No Membership Fee
- Tirzepatide vs Semaglutide: Cost Compared
- Semaglutide pricing comparison table
- Tirzepatide pricing comparison table
- All guides
The numbers behind this page
Checking the figures in this guide
Every price quoted in this guide comes from the programme's own pricing page and carries the date it was captured. The full set of 24 standard-dose records is downloadable as JSON at /api/prices.json, with molecule and dose class stated on every record. Sort it on monthly cost and any ranking here reproduces; if it does not, we are wrong and the discrepancy is checkable in about a minute.
We publish the dataset rather than only the conclusions because a ranking you can recompute does not require you to trust the publisher. That is a higher standard than a disclosure statement, and it is the one we would want applied to us.
Reading the price against the market
Where this sits in the market
The figures in this guide sit inside a market with a measurable shape, and that shape is what makes any single price readable.
12 programmes publish a price for both molecules. Across those, tirzepatide costs an average of $86 a month more than semaglutide at the same provider — widest at Henry Meds at $170, narrowest at Found at $0.
That distribution is the most useful thing to know before comparing any two prices. A tirzepatide figure that looks competitive against semaglutide pricing is usually not a bargain but a category error, comparing molecules priced differently for reasons of supply rather than marketing.
Semaglutide runs $133 to $299 across 12 programmes; tirzepatide $169 to $399 across 12. Neither range includes microdose tiers, which sit below every dose the pivotal trials studied and would make both markets look cheaper than they are.
Where this sits in the market
The figures in this guide sit inside a market with a measurable shape, and that shape is what makes any single price readable.
12 programmes publish a price for both molecules. Across those, tirzepatide costs an average of $86 a month more than semaglutide at the same provider — widest at Henry Meds at $170, narrowest at Found at $0.
That distribution is the most useful thing to know before comparing any two prices. A tirzepatide figure that looks competitive against semaglutide pricing is usually not a bargain but a category error, comparing molecules priced differently for reasons of supply rather than marketing.
Semaglutide runs $133 to $299 across 12 programmes; tirzepatide $169 to $399 across 12. Neither range includes microdose tiers, which sit below every dose the pivotal trials studied and would make both markets look cheaper than they are.
Questions this page answers
Where do these prices come from?
Each is read from the programme's own published pricing page and carries its capture date. The full set of 24 standard-dose records is at /api/prices.json with molecule and dose class on every record.
What is the cheapest verified GLP-1 programme?
Oak Longevity at $133 a month for semaglutide and Found at $169 for tirzepatide, both at standard therapeutic dosing.
Are compounded GLP-1 medicines FDA-approved?
No. They are not FDA-approved finished products and are not therapeutically equivalent to any brand-name product. FDA does not review them for safety, effectiveness or manufacturing quality before marketing.
Why do the same programmes quote two different prices?
Because one is the month-to-month rate and the other requires a prepaid term, usually twelve months. We rank on the month-to-month figure and state the prepaid rate separately, since a rate requiring a year's commitment is not the same offer.